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PRME 424B5: Secondary offering

Filed with the SEC on · accession 0001628280-26-073125

PRME filed a 424B5 (prospectus (offering)) with the SEC on Nov 12, 2026. Prime Medicine, Inc. is offering 35,714,286 shares of common stock at $3.50 per share, raising approximately $125 million in gross proceeds.

Summary of the filing

Prime Medicine, Inc. is offering 35,714,286 shares of common stock at $3.50 per share, raising approximately $125 million in gross proceeds. The offering is being underwritten by Jefferies, TD Cowen, and Goldman Sachs, with an option for underwriters to purchase up to an additional 5,357,142 shares.

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Key details

Public offering price per share$4
Total gross proceeds from offering$125.0M
Underwriting discounts and commissions per share$0
Total underwriting discounts and commissions$7.5M
Net proceeds before expenses to issuer$117.5M
Additional shares option for underwritersshares 5.4M
IssuerPrime Medicine, Inc.
Joint book-running managerJefferies
Joint book-running managerTD Cowen
Joint book-running managerGoldman Sachs & Co. LLC
Passive book-running managerOppenheimer & Co.
Passive book-running managerLifeSci Capital

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Frequently asked questions

What did PRME file with the SEC on Nov 12, 2026?

PRME filed a 424B5 (Secondary offering). Prime Medicine, Inc. is offering 35,714,286 shares of common stock at $3.50 per share, raising approximately $125 million in gross proceeds. The offering is being underwritten by Jefferies, TD Cowen, and Goldman Sachs, with an option for underwriters to purchase up to an additional 5,357,142 shares.

What does a secondary offering mean for PRME stock?

New shares dilute existing holders and are often sold at a discount to the market price.

How do I read a 424B5?

The final terms of an offering of shares or bonds. Look at price, number of shares and the discount to the market price. Large offerings dilute existing shareholders.

Why are SEC filings important?

Public companies must tell the SEC about anything that can change their value — results, leadership changes, big deals, new shares, bankruptcy. Filings are the official source, often before the news. A 424B5 (prospectus (offering)): The final terms of an offering of shares or bonds.

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