AnalysisNews

PRME today

$3.81-$0.49 (-11.33%)close Nov 12, 2026

Trend

DailyDowntrend (starting)

4 hourLeaning Bullish

1 hourStrong Bearish

15 minStrong Bearish

5 minStrong Bearish

Daily trend turns up above $21.67

Key levels

Resistance$18.26

Resistance$17.66

Latest news & SEC filings

DealPrime Medicine Sets Terms for Common Stock Sale to the Public

DealPrime Medicine Proposes $125 Million Public Stock Offering

DealPrime Medicine starts $125M common stock offering

All PRME news →

About Prime Medicine

Prime Medicine is a biotechnology company developing genetic medicines based on Prime Editing, a gene editing technology that makes targeted changes to DNA without double-stranded breaks. Its pipeline includes in vivo programs for liver diseases such as Wilson disease and alpha-1 antitrypsin deficiency, cystic fibrosis programs, and an ex vivo program for chronic granulomatous disease. The company also collaborates with Bristol-Myers Squibb on ex vivo T-cell engineering and with the Cystic Fibrosis Foundation. It operates in the United States.

Based on the company's 10-K filed Mar 3, 2026.

Nasdaq · Healthcare

Prime Medicine, Inc. (PRME)

$3.81-0.49 (-11.33%)
WATCHLISTGrade: BRisk: HIGH
1D5D1M1Y5YMaxSign up for all timeframes
3.463.934.414.883.81Oct 12Oct 20Oct 28Nov 5
High4.15
Low3.77
Open4.04
Volume682K
Avg Vol5.54M
VWAP3.91
30d High5.36
30d Low2.98
30d Chg+27.95%

What Is the Price Target for PRME?

SEPT Low Target

$7.65

SEPT Mid Target

$9.00

SEPT High Target

$10.35

Analyst Consensus

$9.00

Current: $4.22Upside: +113.3%Confidence: 65%Method: Analyst Consensus

Is PRME a Buy or Sell Right Now?

60
Investability Score
WATCHLIST12-18 months

Thesis

  • •Revenue growing 55.3% YoY with UNKNOWN trend — consistent growth.

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Is PRME Overvalued or Undervalued?

Valuation Verdict

FAIR

Methods Used

P/B, Analyst Consensus

Fair Value

$6.88

7

Moat Score

NONE

3/9

Piotroski Score

-3.0

Altman Z-Score

What Is Smart Money Doing with PRME?

Insider Signal

NEUTRAL

0 buys / 0 sells (90d)

Congress Signal

NEUTRAL

0 buys / 0 sells (90d)

Institutional

ACCUMULATING

Short Squeeze Risk

HIGH

Signal: HIGH_SHORT_INTEREST

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PRME Growth Story

Revenue YoY

55.3%

3yr Revenue CAGR

N/A%

EPS Growth YoY

18.18%

FCF Growth YoY

-28.4%

Revenue Trend

UNKNOWN

Dark Pool Trades for PRME

PREVIEW

SEPT Investing tracks real-time dark pool institutional trades for PRME, including block trade sizes, dollar values, and buy/sell side classification. Dark pool trades reveal where institutional investors are positioning before moves become visible on public exchanges.

TimePriceSizeValueSide
14:42:51$3.835,000$$19KMIDPOINT
14:42:37$3.831,002$$4KBUY
14:42:34$3.861,000$$4KBUY
14:42:30$3.851,500$$6KSELL
14:42:10$3.871,000$$4KMIDPOINT

5 dark pool trades shown · $$36K preview volume

Real-time institutional flow, block trades, and net positioning

See all dark pool activity

Full AI Research Report

SEPT's Trading AI has generated a free, downloadable PDF research report for Prime Medicine, Inc. (PRME) covering valuation analysis, financial health assessment, growth projections, smart money tracking, earnings and key price levels. For research only, not investment advice.

Report includes: PDF download, detailed valuation models (DCF, P/E, EV/EBITDA), institutional flow analysis, congress and insider trade tracking, FinBERT news sentiment (1 articles analyzed), and SEC filing intelligence...

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PRME — frequently asked questions

What is PRME stock price today?

Prime Medicine, Inc. (PRME) is at $3.81, down 11.33% (-$0.49) at the Nov 12, 2026 close.

Why is PRME stock moving today?

Latest PRME news — Nov 11, 2026: Prime Medicine Sets Terms for Common Stock Sale to the Public · Nov 10, 2026: Prime Medicine Proposes $125 Million Public Stock Offering

What is the PRME price target?

The average analyst price target for PRME is $9.00, ranging from $8 to $9, based on 3 analysts. Latest: BMO Capital initiates on Aug 19, 2026.

What do analysts rate PRME?

Analyst ratings for PRME: 1 Buy, 2 Hold, 0 Sell — consensus Hold.

Did PRME beat earnings?

PRME last reported on Aug 6, 2026: EPS -$0.24 vs -$0.26 expected — a beat of 6.7%.

Does PRME pay a dividend?

PRME does not currently pay a dividend.

What are PRME support and resistance levels?

Resistance: $17.66, $18.26, $19.28.

What are insiders doing with PRME?

Insider activity: NEUTRAL, 0 buys and 0 sells in the last 90 days.

What is the latest news on PRME?

Nov 11, 2026: Prime Medicine Sets Terms for Common Stock Sale to the Public · Nov 10, 2026: Prime Medicine Proposes $125 Million Public Stock Offering · Nov 10, 2026: Prime Medicine starts $125M common stock offering