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KPTI SCHEDULE 13G: SEC filing

Integrated Core Strategies (US) LLC and affiliated Millennium entities

Filed with the SEC on · accession 0001104659-26-105556

KPTI filed a SCHEDULE 13G (schedule 13g) with the SEC on Sep 4, 2026. Integrated Core Strategies (US) LLC and affiliated Millennium entities filed a Schedule 13G disclosing beneficial ownership of 1,297,297 shares, or 5.7%, of Karyopharm Therapeutics common stock as of August 31, 2026. The stock moved +1.1% by the first close after the filing.

Summary of the filing

Integrated Core Strategies (US) LLC and affiliated Millennium entities filed a Schedule 13G disclosing beneficial ownership of 1,297,297 shares, or 5.7%, of Karyopharm Therapeutics common stock as of August 31, 2026. The filing is a passive investment disclosure under Rule 13d-1(c).

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Key details

Shares beneficially owned$1.3M
Percent of class beneficially owned$6
IssuerKaryopharm Therapeutics Inc.
Reporting person / beneficial ownerIntegrated Core Strategies (US) LLC
Reporting person / affiliated investment managerMillennium Management LLC
Reporting person / managing member of millennium management llcMillennium Group Management LLC
Sole voting trustee of managing member of millennium group management llcIsrael A. Englander
Global general counsel, millennium management llcGil Raviv

How KPTI stock reacted

Close before

$1.77

Sep 3, 2026

First close after

+1.13%

$1.79

5 trading days

-9.04%

$1.61

Since filing

-96.90%

$0.05

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Frequently asked questions

What did KPTI file with the SEC on Sep 4, 2026?

KPTI filed a SCHEDULE 13G (SEC filing). Integrated Core Strategies (US) LLC and affiliated Millennium entities filed a Schedule 13G disclosing beneficial ownership of 1,297,297 shares, or 5.7%, of Karyopharm Therapeutics common stock as of August 31, 2026. The filing is a passive investment disclosure under Rule 13d-1(c).

How do I read a SCHEDULE 13G?

A report the company filed with the SEC (the US market regulator). Start with the summary, then the key amounts and names. Compare it with the company’s earlier filings.

Why are SEC filings important?

Public companies must tell the SEC about anything that can change their value — results, leadership changes, big deals, new shares, bankruptcy. Filings are the official source, often before the news. A SCHEDULE 13G (schedule 13g): A report the company filed with the SEC (the US market regulator).

How did KPTI stock react to this filing?

KPTI closed at $1.77 before the filing and $1.79 on Sep 4, 2026 (+1.13%). Five trading days later: $1.61 (-9.04%).

Other KPTI SEC filings

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