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KPTI SCHEDULE 13G/A: SEC filing

Millennium Management LLC and affiliated entities

Filed with the SEC on · accession 0001104659-26-119710

KPTI filed a SCHEDULE 13G/A (schedule 13g/a) with the SEC on Oct 28, 2026. A report the company filed with the SEC (the US market regulator). The stock moved +73.4% by the first close after the filing.

Summary of the filing

Millennium Management LLC and affiliated entities filed a joint filing agreement as part of a Schedule 13G/A regarding beneficial ownership of Karyopharm Therapeutics common stock.

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Key details

IssuerKaryopharm Therapeutics Inc.
FilerIntegrated Core Strategies (US) LLC
FilerMillennium Management LLC
FilerMillennium Group Management LLC
Global general counselGil Raviv
Individual filerIsrael A. Englander

How KPTI stock reacted

Close before

$0.48

Oct 27, 2026

First close after

+73.35%

$0.83

5 trading days

-81.60%

$0.09

Since filing

-88.56%

$0.05

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Frequently asked questions

What did KPTI file with the SEC on Oct 28, 2026?

KPTI filed a SCHEDULE 13G/A (SEC filing). Millennium Management LLC and affiliated entities filed a joint filing agreement as part of a Schedule 13G/A regarding beneficial ownership of Karyopharm Therapeutics common stock.

How do I read a SCHEDULE 13G/A?

A report the company filed with the SEC (the US market regulator). Start with the summary, then the key amounts and names. Compare it with the company’s earlier filings.

Why are SEC filings important?

Public companies must tell the SEC about anything that can change their value — results, leadership changes, big deals, new shares, bankruptcy. Filings are the official source, often before the news. A SCHEDULE 13G/A (schedule 13g/a): A report the company filed with the SEC (the US market regulator).

How did KPTI stock react to this filing?

KPTI closed at $0.48 before the filing and $0.83 on Oct 28, 2026 (+73.35%). Five trading days later: $0.09 (-81.60%).

Other KPTI SEC filings

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