KPTI SCHEDULE 13G/A: SEC filing

Adage Capital Management, L.P.

Filed with the SEC on Nov 12, 2026 · accession 0000919574-26-007570

KPTI filed a SCHEDULE 13G/A (schedule 13g/a) with the SEC on Nov 12, 2026. Adage Capital Management, L.P. filed an amended Schedule 13G reporting beneficial ownership of 8.87% of Karyopharm Therapeutics Inc.'s common stock, including shares issuable upon exercise of warrants.

Summary of the filing

Adage Capital Management, L.P. filed an amended Schedule 13G reporting beneficial ownership of 8.87% of Karyopharm Therapeutics Inc.'s common stock, including shares issuable upon exercise of warrants. The filing is a passive investment disclosure with no stated intent to influence control of the company.

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Key details

Shares of common stock beneficially owned$2.0M

Percentage of class beneficially ownedPCT 9

Reporting person / beneficial ownerAdage Capital Management, L.P.

IssuerKaryopharm Therapeutics Inc.

Managing member of adage capital advisors, l.l.c. and adage capital partners, l.l.c.Robert Atchinson

Managing member of adage capital advisors, l.l.c. and adage capital partners, l.l.c.Phillip Gross

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Frequently asked questions

What did KPTI file with the SEC on Nov 12, 2026?

KPTI filed a SCHEDULE 13G/A (SEC filing). Adage Capital Management, L.P. filed an amended Schedule 13G reporting beneficial ownership of 8.87% of Karyopharm Therapeutics Inc.'s common stock, including shares issuable upon exercise of warrants. The filing is a passive investment disclosure with no stated intent to influence control of the company.

How do I read a SCHEDULE 13G/A?

A report the company filed with the SEC (the US market regulator). Start with the summary, then the key amounts and names. Compare it with the company’s earlier filings.

Why are SEC filings important?

Public companies must tell the SEC about anything that can change their value — results, leadership changes, big deals, new shares, bankruptcy. Filings are the official source, often before the news. A SCHEDULE 13G/A (schedule 13g/a): A report the company filed with the SEC (the US market regulator).

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