AnalysisNews

XLO today

$8.24-$0.23 (-2.72%)close Nov 12, 2026

Trend

DailyDowntrend (confirmed)

4 hourExpanding

1 hourStrong Bearish

15 minBearish

5 minStrong Bullish

Daily trend turns up above $19.32

Key levels

Resistance$9.00

Resistance$8.33

Support$7.05

Latest news & SEC filings

EarningsXilio Therapeutics Posts Q3 2026 Results, Gives Pipeline Update

EarningsXilio Therapeutics posts smaller Q3 loss, revenue above estimates

SEC FilingXilio Therapeutics, Inc. filed a report on a major company event (Form 8-K)

All XLO news →

About Xilio Therapeutics

Xilio Therapeutics is a clinical-stage biotechnology company that creates cancer immunotherapies engineered to become active only inside tumors. Its pipeline includes an IL-12 candidate, a dual-targeting antibody-cytokine fusion protein, and T cell engagers aimed at solid tumors. The company works with AbbVie and Gilead through collaboration and license agreements and is based in the United States.

Based on the company's 10-K filed Mar 23, 2026.

Nasdaq · Healthcare

Xilio Therapeutics, Inc. (XLO)

$8.24-0.23 (-2.72%)
WATCHLISTGrade: B+Risk: HIGH
1D5D1M1Y5YMaxSign up for all timeframes
7.698.078.468.848.24Oct 12Oct 20Oct 28Nov 5
High8.25
Low7.96
Open8.25
Volume7K
Avg Vol12K
VWAP8.09
30d High9.22
30d Low7.31
30d Chg-8.04%

What Is the Price Target for XLO?

SEPT Low Target

$16.00

SEPT Mid Target

$16.00

SEPT High Target

$16.00

Analyst Consensus

$16.00

Current: $8.47Upside: +88.9%Confidence: 40%Method: Analyst Consensus

Is XLO a Buy or Sell Right Now?

66
Investability Score
WATCHLIST12-18 months
News summary · last 30 days
Nov 10NeutralEarnings3 articles
Xilio Therapeutics reported Q3 2026 results, posting a narrower-than-expected loss of $0.30 per share versus the $0.82 loss analysts anticipated, while revenue of $9.984 million came in well above the $4.840 million estimate. The company also provided a pipeline update and filed a Form 8-K disclosing a major company event. Despite the bullish earnings beat, the stock closed down 3.29% at $8.53, near its low of the day on light volume of 2,268 shares. The negative price action suggests the market may have already priced in the earnings beat or is reacting to other details in the pipeline update or 8-K filing.
Oct 26▲ UpProduct2 articles
Xilio Therapeutics announced that the first patient has been dosed in a Phase 1/2 trial of its drug candidate XTX501, marking the start of human testing in advanced non-small cell lung cancer. Despite this bullish product milestone, the stock closed down 3.05% at $7.31, trading in a wide range between a high of $8.64 and a low of $7.05 on volume of 29,506. The positive clinical news may not have been enough to offset broader selling pressure or profit-taking, as the shares ended near the lower end of the day's range. The direction signal from the news is up, given the medium-impact bullish catalyst of advancing a pipeline asset into the clinic.

Thesis

  • •Revenue growing 589.9% YoY with UNKNOWN trend — consistent growth.

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Is XLO Overvalued or Undervalued?

Valuation Verdict

UNDERVALUED

Methods Used

Analyst Consensus

Fair Value

$16.00

0

Moat Score

NONE

4/9

Piotroski Score

-3.3

Altman Z-Score

What Is Smart Money Doing with XLO?

Insider Signal

NEUTRAL

1 buys / 0 sells (90d)

Congress Signal

NEUTRAL

0 buys / 0 sells (90d)

Institutional

N/A

Short Squeeze Risk

HIGH

Signal: HIGH_SHORT_INTEREST

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XLO Growth Story

Revenue YoY

589.9%

3yr Revenue CAGR

N/A%

EPS Growth YoY

72.51%

FCF Growth YoY

70.1%

Revenue Trend

UNKNOWN

Dark Pool Trades for XLO

PREVIEW

SEPT Investing tracks real-time dark pool institutional trades for XLO, including block trade sizes, dollar values, and buy/sell side classification. Dark pool trades reveal where institutional investors are positioning before moves become visible on public exchanges.

TimePriceSizeValueSide
20:13:32$8.131,001$$8KSELL
15:58:08$7.961,649$$13KSELL
20:15:00$8.201,000$$8KSELL
19:34:20$8.611,500$$13KBUY
16:29:43$8.481,000$$8KMIDPOINT

5 dark pool trades shown · $$51K preview volume

Real-time institutional flow, block trades, and net positioning

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Full AI Research Report

SEPT's Trading AI has generated a free, downloadable PDF research report for Xilio Therapeutics, Inc. (XLO) covering valuation analysis, financial health assessment, growth projections, smart money tracking, earnings and key price levels. For research only, not investment advice.

Report includes: PDF download, detailed valuation models (DCF, P/E, EV/EBITDA), institutional flow analysis, congress and insider trade tracking, FinBERT news sentiment (3 articles analyzed), and SEC filing intelligence...

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XLO — frequently asked questions

What is XLO stock price today?

Xilio Therapeutics, Inc. (XLO) is at $8.24, down 2.72% (-$0.23) at the Nov 12, 2026 close.

Why is XLO stock moving today?

Latest XLO news — Nov 10, 2026: Xilio Therapeutics Posts Q3 2026 Results, Gives Pipeline Update · Nov 10, 2026: Xilio Therapeutics posts smaller Q3 loss, revenue above estimates

Why did XLO stock move on Nov 10, 2026?

Xilio Therapeutics reported Q3 2026 results, posting a narrower-than-expected loss of $0.30 per share versus the $0.82 loss analysts anticipated, while revenue of $9.984 million came in well above the $4.840 million estimate. The company also provided a pipeline update and filed a Form 8-K disclosing a major company event.

What is the XLO price target?

The average analyst price target for XLO is $16.00, ranging from $16 to $16, based on 1 analysts. Latest: Raymond James initiates on Oct 21, 2026.

What do analysts rate XLO?

Analyst ratings for XLO: 0 Buy, 2 Hold, 0 Sell — consensus Hold.

Did XLO beat earnings?

XLO last reported on Nov 12, 2026: EPS -$0.30 vs -$0.82 expected — a beat of 63.4%.

Does XLO pay a dividend?

XLO does not currently pay a dividend.

What are XLO support and resistance levels?

Support: $7.05. Resistance: $8.33, $9.00, $9.67.

What are insiders doing with XLO?

Insider activity: NEUTRAL, 1 buys and 0 sells in the last 90 days.

What is the latest news on XLO?

Nov 10, 2026: Xilio Therapeutics Posts Q3 2026 Results, Gives Pipeline Update · Nov 10, 2026: Xilio Therapeutics posts smaller Q3 loss, revenue above estimates · Nov 10, 2026: Xilio Therapeutics, Inc. filed a report on a major company event (Form 8-K)