SPRO today
$1.02+$0.00 (+0.00%)close Nov 12, 2026Trend
DailyDowntrend (starting)
4 hourStrong Bearish
1 hourStrong Bullish
15 minLeaning Bullish
5 minStrong Bearish
Daily trend turns up above $3.18
Key levels
Resistance$1.18
Resistance$1.04
Support$0.96
Support$0.83
Latest news & SEC filings
NewsSpero Therapeutics seats new director on its board
SEC FilingSpero Therapeutics, Inc. filed an insider trading report (Form 4)
SEC FilingSpero Therapeutics, Inc. filed a report on a major company event (Form 8-K)
All SPRO news →About Spero Therapeutics
Spero Therapeutics is a biopharmaceutical firm in the clinical stage of development, working on therapies for uncommon illnesses and infections where medical need remains high. Its lead asset is an antibiotic taken by mouth, belonging to the carbapenem family, under development for difficult urinary tract infections affecting grown patients with few pill-based choices; GSK holds rights to develop and sell it across most of the world, excluding select Asian nations. Earlier programs targeting pneumonia acquired in hospitals and lung disease from nontuberculous mycobacteria have been discontinued.
Based on the company's 10-K filed Mar 26, 2026.
Nasdaq · Healthcare
Spero Therapeutics, Inc. (SPRO)
What Is the Price Target for SPRO?
SEPT Low Target
$6.00
SEPT Mid Target
$6.00
SEPT High Target
$6.00
Analyst Consensus
$6.00
Is SPRO a Buy or Sell Right Now?
Thesis
- •Revenue growing 39.2% YoY with STRONG trend — consistent growth.
AI-Powered Trading Signals
Trained on trillions of real market data to read price action and give you a simple, emotionless trading strategy for SPRO.
Start Free Trial →Is SPRO Overvalued or Undervalued?
Valuation Verdict
OVERVALUED
Methods Used
P/B, PEG, Analyst Consensus
Fair Value
$1.95
50
Moat Score
NARROW
5/9
Piotroski Score
-3.1
Altman Z-Score
What Is Smart Money Doing with SPRO?
Insider Signal
SELLING
0 buys / 8 sells (90d)
Congress Signal
NEUTRAL
0 buys / 0 sells (90d)
Institutional
N/A
Short Squeeze Risk
LOW
Signal: NEUTRAL
Recent Insider Activity
| Name | Title | Type | Shares | Value | Date |
|---|---|---|---|---|---|
| Rajavelu Esther | director officer | Sale | 40,851 | $42K | Nov 9, 2026 |
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Revenue YoY
39.2%
3yr Revenue CAGR
7.7%
EPS Growth YoY
111.81%
FCF Growth YoY
N/A%
Revenue Trend
STRONG
Dark Pool Trades for SPRO
PREVIEWSEPT Investing tracks real-time dark pool institutional trades for SPRO, including block trade sizes, dollar values, and buy/sell side classification. Dark pool trades reveal where institutional investors are positioning before moves become visible on public exchanges.
| Time | Price | Size | Value | Side |
|---|---|---|---|---|
| 17:56:24 | $1.02 | 1,300 | $$1K | BUY |
| 17:33:01 | $1.02 | 1,500 | $$2K | BUY |
| 17:32:56 | $1.01 | 1,500 | $$2K | SELL |
| 16:39:37 | $1.01 | 3,800 | $$4K | SELL |
| 16:03:39 | $1.00 | 2,476 | $$2K | SELL |
5 dark pool trades shown · $$11K preview volume
Real-time institutional flow, block trades, and net positioning
Full AI Research Report
SEPT's Trading AI has generated a free, downloadable PDF research report for Spero Therapeutics, Inc. (SPRO) covering valuation analysis, financial health assessment, growth projections, smart money tracking, earnings and key price levels. For research only, not investment advice.
Report includes: PDF download, detailed valuation models (DCF, P/E, EV/EBITDA), institutional flow analysis, congress and insider trade tracking, FinBERT news sentiment (1 articles analyzed), and SEC filing intelligence...
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Trained on trillions of real market data to read price action and give you a simple, emotionless trading strategy. SEPT tells you when to buy, when to sell, and grades every stock so you never trade blind.
Try SEPT Free for 7 Days →SPRO — frequently asked questions
What is SPRO stock price today?
Spero Therapeutics, Inc. (SPRO) is at $1.02, up 0.00% (+$0.00) at the Nov 12, 2026 close.
Why is SPRO stock moving today?
Latest SPRO news — Nov 11, 2026: Spero Therapeutics seats new director on its board · Nov 10, 2026: Spero Therapeutics, Inc. filed an insider trading report (Form 4)
What is the SPRO price target?
The average analyst price target for SPRO is $6.00, ranging from $6 to $6, based on 2 analysts. Latest: Cantor Fitzgerald initiates on Oct 28, 2026.
What do analysts rate SPRO?
Analyst ratings for SPRO: 0 Buy, 2 Hold, 0 Sell — consensus Hold.
Did SPRO beat earnings?
SPRO last reported on Aug 12, 2026: EPS -$0.16 vs -$0.17 expected — a beat of 5.9%.
What is SPRO's P/E ratio?
SPRO trades at a P/E of 7.5 vs a Healthcare average of 17.7.
Does SPRO pay a dividend?
SPRO does not currently pay a dividend.
What are SPRO support and resistance levels?
Support: $0.96, $0.83, $0.74. Resistance: $1.04, $1.18, $1.27.
What are insiders doing with SPRO?
Insider activity: SELLING, 0 buys and 8 sells in the last 90 days.
What is the latest news on SPRO?
Nov 11, 2026: Spero Therapeutics seats new director on its board · Nov 10, 2026: Spero Therapeutics, Inc. filed an insider trading report (Form 4) · Nov 10, 2026: Spero Therapeutics, Inc. filed a report on a major company event (Form 8-K)