SPRB today
$42.89-$3.31 (-7.16%)close Nov 12, 2026Trend
DailyUptrend (confirmed)
4 hourBearish
1 hourStrong Bearish
15 minLeaning Bullish
5 minStrong Bearish
Daily trend turns down below $7.26
Key levels
Resistance$49.85
Resistance$45.65
Support$38.06
Support$12.75
Latest news & SEC filings
NewsSpruce Biosciences spins off CRHX-101 into new company Adrenyx Biosciences
EarningsSpruce Biosciences posts Q3 loss of $8.51 per share
EarningsSpruce Biosciences Posts Q3 2026 Financials
SEC FilingSpruce Biosciences, Inc. filed a report on a major company event (Form 8-K)
NewsSpruce Biosciences to place CRHX-101 assets in new firm Adrenyx, then distribute shares
All SPRB news →About Spruce Biosciences
Spruce Biosciences is a biopharmaceutical company working on treatments for brain and nervous system conditions. Its main candidate, tralesinidase alfa, is a replacement enzyme delivered into the fluid around the spinal cord to treat Sanfilippo Syndrome Type B, or MPS IIIB. The company is also developing tildacerfont and Cortibon for major depressive disorder. It plans to sell products in the United States, Europe, the United Kingdom and other regions.
Based on the company's 10-K filed Mar 9, 2026.
Nasdaq · Healthcare
SPRUCE BIOSCIENCES, INC. (SPRB)
What Is the Price Target for SPRB?
SEPT Low Target
$123.00
SEPT Mid Target
$144.00
SEPT High Target
$160.00
Analyst Consensus
$144.00
Is SPRB a Buy or Sell Right Now?
Thesis
- •Revenue growing -51.3% YoY with UNKNOWN trend — consistent growth.
AI-Powered Trading Signals
Trained on trillions of real market data to read price action and give you a simple, emotionless trading strategy for SPRB.
Start Free Trial →Is SPRB Overvalued or Undervalued?
Valuation Verdict
UNDERVALUED
Methods Used
P/B, Analyst Consensus
Fair Value
$129.16
12
Moat Score
NONE
4/9
Piotroski Score
-7.1
Altman Z-Score
What Is Smart Money Doing with SPRB?
Insider Signal
NEUTRAL
0 buys / 0 sells (90d)
Congress Signal
NEUTRAL
0 buys / 0 sells (90d)
Institutional
N/A
Short Squeeze Risk
HIGH
Signal: HIGH_SHORT_INTEREST
Track Smart Money Across 4,000+ Stocks
Insider trades, congress trades, institutional flows, and short interest — updated daily with real-time alerts.
See All Smart Money Signals →SPRB Growth Story
Revenue YoY
-51.3%
3yr Revenue CAGR
N/A%
EPS Growth YoY
47.27%
FCF Growth YoY
N/A%
Revenue Trend
UNKNOWN
Dark Pool Trades for SPRB
PREVIEWSEPT Investing tracks real-time dark pool institutional trades for SPRB, including block trade sizes, dollar values, and buy/sell side classification. Dark pool trades reveal where institutional investors are positioning before moves become visible on public exchanges.
| Time | Price | Size | Value | Side |
|---|---|---|---|---|
| 15:01:17 | $44.87 | 1,000 | $$45K | SELL |
| 17:25:15 | $46.47 | 5,400 | $$251K | BUY |
| 20:25:20 | $46.10 | 2,000 | $$92K | BUY |
| 20:21:42 | $45.53 | 1,000 | $$46K | MIDPOINT |
| 21:20:00 | $49.34 | 1,164 | $$57K | SELL |
5 dark pool trades shown · $$491K preview volume
Real-time institutional flow, block trades, and net positioning
Full AI Research Report
SEPT's Trading AI has generated a free, downloadable PDF research report for SPRUCE BIOSCIENCES, INC. (SPRB) covering valuation analysis, financial health assessment, growth projections, smart money tracking, earnings and key price levels. For research only, not investment advice.
Report includes: PDF download, detailed valuation models (DCF, P/E, EV/EBITDA), institutional flow analysis, congress and insider trade tracking, FinBERT news sentiment (4 articles analyzed), and SEC filing intelligence...
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Trained on trillions of real market data to read price action and give you a simple, emotionless trading strategy. SEPT tells you when to buy, when to sell, and grades every stock so you never trade blind.
Try SEPT Free for 7 Days →SPRB — frequently asked questions
What is SPRB stock price today?
SPRUCE BIOSCIENCES, INC. (SPRB) is at $42.89, down 7.16% (-$3.31) at the Nov 12, 2026 close.
Why is SPRB stock moving today?
Latest SPRB news — Nov 10, 2026: Spruce Biosciences spins off CRHX-101 into new company Adrenyx Biosciences · Nov 9, 2026: Spruce Biosciences posts Q3 loss of $8.51 per share
What is the SPRB price target?
The average analyst price target for SPRB is $144.00, ranging from $123 to $160, based on 6 analysts.
What do analysts rate SPRB?
Analyst ratings for SPRB: 0 Buy, 8 Hold, 0 Sell — consensus Hold.
Did SPRB beat earnings?
SPRB last reported on Aug 12, 2026: EPS -$6.68 vs -$5.79 expected — a miss of 15.4%.
Does SPRB pay a dividend?
SPRB does not currently pay a dividend.
How much debt does SPRB have?
SPRUCE BIOSCIENCES, INC. reported $20M of debt and $96M of cash (Jun 30, 2026).
What are SPRB support and resistance levels?
Support: $38.06, $12.75, $7.26. Resistance: $45.65, $49.85, $55.34.
What are insiders doing with SPRB?
Insider activity: NEUTRAL, 0 buys and 0 sells in the last 90 days.
What is the latest news on SPRB?
Nov 10, 2026: Spruce Biosciences spins off CRHX-101 into new company Adrenyx Biosciences · Nov 9, 2026: Spruce Biosciences posts Q3 loss of $8.51 per share · Nov 9, 2026: Spruce Biosciences Posts Q3 2026 Financials