AnalysisNews

SION today

$3.43-$0.27 (-7.30%)close Nov 12, 2026

Trend

DailyDowntrend (confirmed)

4 hourStrong Bearish

1 hourStrong Bearish

15 minSymmetric Triangle

5 minStrong Bearish

Daily trend turns up above $4.16

Key levels

Resistance$4.31

Resistance$3.85

Support$3.19

Latest news & SEC filings

EarningsSionna Therapeutics Posts Q3 2026 Results, Business Update

EarningsSionna Therapeutics posts quarterly loss of $0.72 per share

SEC FilingSionna Therapeutics, Inc. filed a report on a major company event (Form 8-K)

All SION news →

About Sionna Therapeutics

Sionna Therapeutics is a drug developer focused on cystic fibrosis, a genetic disease affecting the lungs and other organs. The company creates small molecules intended to stabilize a part of the CFTR protein called NBD1, aiming to restore its function. Its main candidates include SION-719 and SION-451, along with other compounds that target different regions of CFTR. These are being studied in human trials, both alongside approved CF medicines and in company-developed combinations, for people who carry the F508del mutation.

Based on the company's 10-K filed Mar 2, 2026.

Nasdaq · Healthcare

Sionna Therapeutics, Inc. (SION)

$3.43-0.27 (-7.30%)
WATCHLISTGrade: BRisk: LOW
1D5D1M1Y5YMaxSign up for all timeframes
3.613.934.264.583.43Oct 12Oct 20Oct 28Nov 5
High3.66
Low3.39
Open3.66
Volume383K
Avg Vol927K
VWAP3.47
30d High4.91
30d Low3.28
30d Chg-30.14%

What Is the Price Target for SION?

SEPT Low Target

$6.00

SEPT Mid Target

$6.00

SEPT High Target

$6.00

Analyst Consensus

$6.00

Current: $3.43Upside: +74.9%Confidence: 40%Method: Analyst Consensus

Is SION a Buy or Sell Right Now?

63
Investability Score
WATCHLIST12-18 months

Thesis

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    Is SION Overvalued or Undervalued?

    Valuation Verdict

    UNDERVALUED

    Methods Used

    P/B, Analyst Consensus

    Fair Value

    $8.31

    12

    Moat Score

    NONE

    4/9

    Piotroski Score

    3.0

    Altman Z-Score

    What Is Smart Money Doing with SION?

    Insider Signal

    SELLING

    0 buys / 14 sells (90d)

    Congress Signal

    NEUTRAL

    0 buys / 0 sells (90d)

    Institutional

    N/A

    Short Squeeze Risk

    MEDIUM

    Signal: NEUTRAL

    Recent Insider Activity

    NameTitleTypeSharesValueDate
    Ridloff ElenaofficerBuy47,269-Sep 17, 2026
    Ridloff ElenaofficerBuy47,268-Sep 17, 2026
    Cloonan Michaeldirector officerBuy109,025-Sep 17, 2026
    Fitzpatrick JenniferofficerBuy28,133-Sep 17, 2026
    Fitzpatrick JenniferofficerBuy28,132-Sep 17, 2026
    McKee CharlotteofficerBuy50,000-Sep 17, 2026
    RA CAPITAL MANAGEMENT, L.P.director 10% ownerSale3,415,011$21.6MSep 17, 2026
    RA CAPITAL MANAGEMENT, L.P.director 10% ownerSale33,800$252KSep 17, 2026
    Thompson Peter A.directorSale101$4KMay 27, 2026
    ORBIMED ADVISORS LLCdirectorSale101$4KMay 27, 2026

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    SION Growth Story

    Revenue YoY

    N/A%

    3yr Revenue CAGR

    N/A%

    EPS Growth YoY

    88.24%

    FCF Growth YoY

    -26.2%

    Revenue Trend

    UNKNOWN

    Dark Pool Trades for SION

    PREVIEW

    SEPT Investing tracks real-time dark pool institutional trades for SION, including block trade sizes, dollar values, and buy/sell side classification. Dark pool trades reveal where institutional investors are positioning before moves become visible on public exchanges.

    TimePriceSizeValueSide
    21:26:17$3.433,182$$11KSELL
    21:01:26$3.432,006$$7KSELL
    21:00:25$3.433,806$$13KSELL
    21:00:25$3.433,588$$12KSELL
    20:58:37$3.421,500$$5KBUY

    5 dark pool trades shown · $$48K preview volume

    Real-time institutional flow, block trades, and net positioning

    See all dark pool activity

    Full AI Research Report

    SEPT's Trading AI has generated a free, downloadable PDF research report for Sionna Therapeutics, Inc. (SION) covering valuation analysis, financial health assessment, growth projections, smart money tracking, earnings and key price levels. For research only, not investment advice.

    Report includes: PDF download, detailed valuation models (DCF, P/E, EV/EBITDA), institutional flow analysis, congress and insider trade tracking, FinBERT news sentiment (1 articles analyzed), and SEC filing intelligence...

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    SION — frequently asked questions

    What is SION stock price today?

    Sionna Therapeutics, Inc. (SION) is at $3.43, down 7.30% (-$0.27) at the Nov 12, 2026 close.

    Why is SION stock moving today?

    Latest SION news — Nov 11, 2026: Sionna Therapeutics Posts Q3 2026 Results, Business Update · Nov 10, 2026: Sionna Therapeutics posts quarterly loss of $0.72 per share

    What is the SION price target?

    The average analyst price target for SION is $6.00, ranging from $6 to $6, based on 1 analysts. Latest: Wedbush maintains on Sep 15, 2026.

    What do analysts rate SION?

    Analyst ratings for SION: 0 Buy, 7 Hold, 2 Sell — consensus Hold.

    Did SION beat earnings?

    SION last reported on Aug 6, 2026: EPS -$0.66 vs -$0.65 expected — a miss of 1.5%.

    Does SION pay a dividend?

    SION does not currently pay a dividend.

    What are SION support and resistance levels?

    Support: $3.19. Resistance: $3.85, $4.31, $5.12.

    What are insiders doing with SION?

    Insider activity: SELLING, 0 buys and 14 sells in the last 90 days.

    What is the latest news on SION?

    Nov 11, 2026: Sionna Therapeutics Posts Q3 2026 Results, Business Update · Nov 10, 2026: Sionna Therapeutics posts quarterly loss of $0.72 per share · Nov 10, 2026: Sionna Therapeutics, Inc. filed a report on a major company event (Form 8-K)