Trend
DailyDowntrend (confirmed)
4 hourLeaning Bearish
1 hourLeaning Bearish
15 minBullish
5 minStrong Bullish
Daily trend turns up above $38.73
Key levels
Resistance$51.10
Support$45.60
Support$41.07
Latest news & SEC filings
AnalystStifel keeps Buy rating on Septerna, lifts price target to $60
EarningsSepterna Posts Q3 2026 Results, Notes Business Progress
EarningsSepterna posts wider quarterly loss as revenue falls short
SEC FilingSepterna, Inc. filed a report on a major company event (Form 8-K)
All SEPN news →Septerna is a clinical-stage biotechnology company that develops oral small molecule drugs aimed at G protein-coupled receptors. It uses its proprietary Native Complex Platform to create drug candidates for hormone-related disorders, immune and inflammatory conditions, and disorders of metabolism. The company also collaborates with Novo Nordisk on treatments for metabolic diseases and is based in the United States.
Based on the company's 10-K filed Mar 9, 2026.
Nasdaq · Healthcare
SEPT Low Target
$40.00
SEPT Mid Target
$56.50
SEPT High Target
$65.00
Analyst Consensus
$56.50
Thesis
Trained on trillions of real market data to read price action and give you a simple, emotionless trading strategy for SEPN.
Start Free Trial →Valuation Verdict
OVERVALUED
Methods Used
P/B, Analyst Consensus
Fair Value
$47.65
22
Moat Score
NONE
4/9
Piotroski Score
5.8
Altman Z-Score
Insider Signal
SELLING
0 buys / 11 sells (90d)
Congress Signal
NEUTRAL
0 buys / 0 sells (90d)
Institutional
N/A
Short Squeeze Risk
HIGH
Signal: HIGH_SHORT_INTEREST
| Name | Title | Type | Shares | Value | Date |
|---|---|---|---|---|---|
| Bhatt Elizabeth | officer | Buy | 4,000 | $27K | Oct 15, 2026 |
| Bhatt Elizabeth | officer | Sale | 1,094 | $40K | Oct 15, 2026 |
| Bhatt Elizabeth | officer | Sale | 2,906 | $109K | Oct 15, 2026 |
| Shaikhly Samira | officer | Buy | 4,355 | $7K | Jun 1, 2026 |
| Shaikhly Samira | officer | Buy | 943 | $3K | Jun 1, 2026 |
| Shaikhly Samira | officer | Buy | 637 | $2K | Jun 1, 2026 |
| Shaikhly Samira | officer | Sale | 1,700 | $47K | Jun 1, 2026 |
| Shaikhly Samira | officer | Sale | 1,346 | $39K | Jun 1, 2026 |
| Shaikhly Samira | officer | Sale | 2,889 | $86K | Jun 1, 2026 |
| Shaikhly Samira | officer | Buy | 11,798 | $80K | May 26, 2026 |
Insider trades, congress trades, institutional flows, and short interest — updated daily with real-time alerts.
See All Smart Money Signals →Revenue YoY
4174.5%
3yr Revenue CAGR
N/A%
EPS Growth YoY
84.85%
FCF Growth YoY
257.6%
Revenue Trend
ACCELERATING
SEPT Investing tracks real-time dark pool institutional trades for SEPN, including block trade sizes, dollar values, and buy/sell side classification. Dark pool trades reveal where institutional investors are positioning before moves become visible on public exchanges.
| Time | Price | Size | Value | Side |
|---|---|---|---|---|
| 20:52:24 | $48.66 | 3,000 | $$146K | MIDPOINT |
| 20:51:01 | $49.26 | 1,200 | $$59K | MIDPOINT |
| 20:51:01 | $49.26 | 1,000 | $$49K | MIDPOINT |
| 20:51:00 | $49.35 | 1,100 | $$54K | SELL |
| 20:51:00 | $49.34 | 1,000 | $$49K | MIDPOINT |
5 dark pool trades shown · $$358K preview volume
Real-time institutional flow, block trades, and net positioning
SEPT's Trading AI has generated a free, downloadable PDF research report for Septerna, Inc. (SEPN) covering valuation analysis, financial health assessment, growth projections, smart money tracking, earnings and key price levels. For research only, not investment advice.
Report includes: PDF download, detailed valuation models (DCF, P/E, EV/EBITDA), institutional flow analysis, congress and insider trade tracking, FinBERT news sentiment (2 articles analyzed), and SEC filing intelligence...
Trained on trillions of real market data to read price action and give you a simple, emotionless trading strategy. SEPT tells you when to buy, when to sell, and grades every stock so you never trade blind.
Try SEPT Free for 7 Days →Septerna, Inc. (SEPN) is at $46.52, down 4.19% (-$2.04) at the Nov 12, 2026 close.
Latest SEPN news — Nov 10, 2026: Stifel keeps Buy rating on Septerna, lifts price target to $60 · Nov 9, 2026: Septerna Posts Q3 2026 Results, Notes Business Progress
The average analyst price target for SEPN is $56.50, ranging from $40 to $65, based on 8 analysts. Latest: Guggenheim maintains on Nov 6, 2026.
Analyst ratings for SEPN: 10 Buy, 0 Hold, 0 Sell — consensus Strong Buy.
SEPN last reported on Aug 10, 2026: EPS -$0.29 vs -$0.43 expected — a beat of 31.9%.
SEPN does not currently pay a dividend.
Support: $45.60, $41.07, $38.05. Resistance: $51.10.
Insider activity: SELLING, 0 buys and 11 sells in the last 90 days.
Nov 10, 2026: Stifel keeps Buy rating on Septerna, lifts price target to $60 · Nov 9, 2026: Septerna Posts Q3 2026 Results, Notes Business Progress · Nov 9, 2026: Septerna posts wider quarterly loss as revenue falls short