AnalysisNews

PYXS today

$1.53-$0.05 (-3.16%)close Nov 13, 2026

Trend

DailyDowntrend (starting)

4 hourStrong Bearish

1 hourDescending Triangle

15 minSymmetric Triangle

5 minDescending Triangle

Daily trend turns up above $5.55

Key levels

Resistance$1.99

Resistance$1.79

Support$1.50

Support$1.26

Latest news & SEC filings

AnalystRBC Capital Markets keeps Outperform rating on Pyxis Oncology, lifts price target

SEC FilingPyxis Oncology, Inc. filed an insider trading report (Form 4)

AnalystRBC Capital keeps Outperform rating on Pyxis Oncology, lifts target to $7

AnalystWedbush keeps Outperform rating on Pyxis Oncology, cuts price target to $7

All PYXS news →

About Pyxis Oncology

Pyxis Oncology is a clinical-stage oncology company creating therapies for solid tumors, concentrating first on cancers of the head and neck. Its main candidate, micvotabart pelidotin, is an antibody-drug conjugate aimed at a fibronectin variant present in the tumor microenvironment. The company is studying this candidate alone and alongside pembrolizumab in trials conducted in the United States, Europe, and other regions.

Based on the company's 10-K filed Mar 23, 2026.

Nasdaq · Healthcare

Pyxis Oncology, Inc. (PYXS)

$1.53-0.05 (-3.16%)
WATCHLISTGrade: BRisk: LOW
1D5D1M1Y5YMaxSign up for all timeframes
1.671.811.962.101.53Oct 13Oct 21Oct 29Nov 6
High1.60
Low1.51
Open1.57
Volume117K
Avg Vol830K
VWAP1.53
30d High2.24
30d Low1.53
30d Chg-31.70%

What Is the Price Target for PYXS?

SEPT Low Target

$7.00

SEPT Mid Target

$7.00

SEPT High Target

$12.00

Analyst Consensus

$7.00

Current: $1.63Upside: +329.4%Confidence: 85%Method: Analyst Consensus

Is PYXS a Buy or Sell Right Now?

61
Investability Score
WATCHLIST12-18 months
News summary · last 30 days
Oct 27▲ UpProduct2 articles
Pyxis Oncology shares closed at $1.84, up 8.24% on volume of 1,171,380, after the company announced that micvotabart pelidotin (MICVO) data will be featured in a late-breaking oral presentation at the EORTC-NCI-AACR Symposium. The presentation will cover MICVO monotherapy results in patients with previously treated recurrent or metastatic head and neck cancer, though the company did not disclose the actual study results in the announcement. The positive price move suggests investors are anticipating favorable data from the upcoming oral session. The news serves as a bullish catalyst for the stock, with the direction signal pointing up.

Thesis

  • •Revenue growing -14.2% YoY with UNKNOWN trend — consistent growth.

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Is PYXS Overvalued or Undervalued?

Valuation Verdict

UNDERVALUED

Methods Used

P/B, Analyst Consensus

Fair Value

$5.55

7

Moat Score

NONE

2/9

Piotroski Score

-7.4

Altman Z-Score

What Is Smart Money Doing with PYXS?

Insider Signal

NEUTRAL

0 buys / 3 sells (90d)

Congress Signal

NEUTRAL

0 buys / 0 sells (90d)

Institutional

N/A

Short Squeeze Risk

MEDIUM

Signal: NEUTRAL

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PYXS Growth Story

Revenue YoY

-14.2%

3yr Revenue CAGR

N/A%

EPS Growth YoY

3.03%

FCF Growth YoY

-9.7%

Revenue Trend

UNKNOWN

Dark Pool Trades for PYXS

PREVIEW

SEPT Investing tracks real-time dark pool institutional trades for PYXS, including block trade sizes, dollar values, and buy/sell side classification. Dark pool trades reveal where institutional investors are positioning before moves become visible on public exchanges.

TimePriceSizeValueSide
16:35:00$1.532,883$$4KSELL
16:13:57$1.529,000$$14KBUY
15:18:04$1.542,000$$3KSELL
15:05:17$1.535,645$$9KSELL
15:05:17$1.533,097$$5KSELL

5 dark pool trades shown · $$35K preview volume

Real-time institutional flow, block trades, and net positioning

See all dark pool activity

Full AI Research Report

SEPT's Trading AI has generated a free, downloadable PDF research report for Pyxis Oncology, Inc. (PYXS) covering valuation analysis, financial health assessment, growth projections, smart money tracking, earnings and key price levels. For research only, not investment advice.

Report includes: PDF download, detailed valuation models (DCF, P/E, EV/EBITDA), institutional flow analysis, congress and insider trade tracking, FinBERT news sentiment (1 articles analyzed), and SEC filing intelligence...

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PYXS — frequently asked questions

What is PYXS stock price today?

Pyxis Oncology, Inc. (PYXS) is at $1.53, down 3.16% (-$0.05) at the Nov 13, 2026 close.

Why is PYXS stock moving today?

Latest PYXS news — Nov 7, 2026: RBC Capital Markets keeps Outperform rating on Pyxis Oncology, lifts price target · Nov 6, 2026: Pyxis Oncology, Inc. filed an insider trading report (Form 4)

Why did PYXS stock move on Oct 27, 2026?

Pyxis Oncology shares closed at $1.84, up 8.24% on volume of 1,171,380, after the company announced that micvotabart pelidotin (MICVO) data will be featured in a late-breaking oral presentation at the EORTC-NCI-AACR Symposium. The presentation will cover MICVO monotherapy results in patients with previously treated recurrent or metastatic head and neck cancer, though the company did not disclose the actual study results in the announcement.

What is the PYXS price target?

The average analyst price target for PYXS is $7.00, ranging from $7 to $12, based on 5 analysts. Latest: Wedbush maintains on Nov 6, 2026.

What do analysts rate PYXS?

Analyst ratings for PYXS: 0 Buy, 9 Hold, 0 Sell — consensus Hold.

Did PYXS beat earnings?

PYXS last reported on Nov 5, 2026: EPS -$0.24 vs -$0.29 expected — a beat of 17.2%.

Does PYXS pay a dividend?

PYXS does not currently pay a dividend.

What are PYXS support and resistance levels?

Support: $1.50, $1.26, $1.03. Resistance: $1.79, $1.99, $2.18.

What are insiders doing with PYXS?

Insider activity: NEUTRAL, 0 buys and 3 sells in the last 90 days.

What is the latest news on PYXS?

Nov 7, 2026: RBC Capital Markets keeps Outperform rating on Pyxis Oncology, lifts price target · Nov 6, 2026: Pyxis Oncology, Inc. filed an insider trading report (Form 4) · Nov 6, 2026: RBC Capital keeps Outperform rating on Pyxis Oncology, lifts target to $7